Ambient air pollution is one of the most important global risk factors for morbidity, disability and mortality. Because this risk affects a huge number of urban areas in high income as well as in low income countries, the healthcare dimensions of its consequences are huge, as one realizes considering that there are at least 7 million premature deaths due to air pollution, according to WHO and the Global Burden of Disease epidemiological study.

Living in one of the most polluted area of the world (the Po River Plain), together with the distinguished epidemiologists of the Regione Lazio (led by Francesco Forastiere) and a former staff member of WHO (Michal Krzyzanowski), we first chose in 2015 to organize an independent international seminar called RespiraMi, with the goal to gather the most distinguished global experts and ask them to present their recent and mostly unpublished data on the progress of science towards tackling the global problem of outdoor and indoor air pollution, in the frame of a two days seminar. The third 2019 edition of the Seminar (RespiraMi 3) enlists a distinguish team of expert speakers from the 4 world continents, who will put special emphasis on the effects of air pollution on the weakest groups of citizens: the child, the pregnant woman, older people, to poorest people as well as on the growing evidence that air pollution is one of the causes of most common, growing and devastating neurodegenerative disease (dementia, Alzheimer). The Seminar will newly deal also on the arrays of measures that are being enforced in highly polluted countries such as China, Poland and also Italy to mitigate the deleterious effects of outdoor and indoor air pollutants. Finally, special emphasis will be given to recent data that convincingly show that living, working and going to school in areas richer in greenness decrease overall mortality (particularly from cancer and cardiopulmonary diseases) but also allows school children to achieve better learning performances than those who live and go to school in areas deprived of greenness.

P.M. Mannucci     S. Harari     F. Forastiere     M. Krzyzanowski






Thursday, 24 January 2019 - Afternoon




Opening – Welcome Addresses

Stefano Boeri – President of Fondazione La Triennale di Milano (Milan, IT)

Silvano Bosari – Scientific Director, of Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico (Milan, IT)


New evidence on health effects of air pollution

Chairs :            F. Forastiere (Rome, IT) - S. Harari (Milan, IT)



Zorana Andersen (Copenhagen, DK)

Exposure to air pollution and cancer risk



Francesco Forastiere (Rome, IT)

Updates on the cardiovascular effects of air pollution







Sergio Harari (Milan, IT)

Updates on the respiratory effects of air pollution


Panel Discussion



Coffee Break


Chairs: A. Peters (Munich, DE) - M.C. Facchini (Bologna, IT)



Monica Guxens (Barcelona, ES)

Early life air pollution exposure, neuropsychological development and neuroimaging in children



Annette Peters (Munich, DE)

Environmental exposure and disease: role of the epigenome



Frank Kelly (London, UK)

Mechanisms of particulate matter (PM) toxicity


18:40 - 19:10    Panel Discussion


19.10 – 19.40 – Closing Remarks




Friday, 25 January 2019 - Morning



Health effects of very low and very high PM levels

Chairs:                    G. Hoek (Utrecht, NL) - H. Kan (Shanghai, CN)



Gerard Hoek (Utrecht, NL)

Combining evidence from studies on the effects of air pollution at low level



Haidong Kan (Shanghai, CN)

Evidence on the health risks from highly polluted regions



Michela Baccini (Florence, IT)

Causal approaches to study the effects of air pollution




Coffee Break




Understanding impact of PM components and sources

Chairs:                      B. Hoffmann (Dusseldorf, DE) - X. Querol (Barcelona, ES)



Jason Sacks (Durham NC, USA)

Systematic review of health effects of PM components



Barbara Hoffmann (Dusseldorf, DE)

Ultrafine particles and health effects



Xavier Querol (Barcelona, ES)

AIRUSE-LIFE PMx source apportionment and measures to abate urban air pollution in

Southern Europe







13:00 – 14:00

Fulvio Amato (Barcelona, ES)

Non-exhaust emissions: sources and health effects










Friday, 25 January 2019 - Afternoon


Research on air pollution and health in Italy

Chairs :                            M. Stafoggia (Rome, IT) - G. Cesaroni (Rome, IT)



Giovanni Viegi (Palermo, IT)

The Beep project




Massimo Stafoggia (Rome, IT)

Fine resolved daily PM maps in Italy using satellite data




Giulia Cesaroni (Rome, IT)

New evidence from the Rome Longitudinal Study




Franca Rusconi (Florence, IT)

Air pollution and health effects in children: the Piccoli più project




Carla Ancona (Rome, IT)

Noise and air pollution: mapping and incidence of diseases




Andrea Ranzi (Modena, IT)

Particulate matter components, sources and health effects






Coffee Break


A. Miani (Milan, IT) - P. Michelozzi (Rome, IT)




Lucia Bisceglia (Bari, IT)

Industrial pollution and health: experience from the Apulia Region




Sara Conti (Milan, IT)

Studying the health effects of air pollution in Lombardy?




Paola Michelozzi (Rome, IT)

The Italian Surveillance system on temperature and air pollution




Open discussion:


What is missing in research on the health effects of air pollution in Italy?








Saturday, 26 January 2019 - Morning




Using evidence to support policies addressing health risks of air pollution

Chairs :                    S. Gumy (Geneva, CH) - M. Krzyzanowski (Warsaw, PL)



Michal Krzyzanowski (Warsaw, PL)

Approaches and challenges in estimating the health impact of air pollution



Sophie Gumy (Geneva, CH)

The WHO worldwide impact estimates for 2016



Pier Mannuccio Mannucci (Milan, IT)

Greenness to mitigate the health effects of air pollution



Markus Amann (Laxenburg, A)

Challenges in sector-specific emission reductions in Europe:  short- and long-time perspectives




Coffee Break



Richard Ballaman (Bern, CH)

Policy issues: progress made and remaining challenges in neighboring countries






Vicente Franco (Brussels, B)

The EU Directive: time for “fitness check?”


Involving people in air pollution risk reduction (round table discussion)

Chairs:                     P.M. Mannucci (Milan, IT) - S. Harari (Milan, IT) – F. Forastiere (Rome, IT)



Ugo Taddei (Brussels, B)

The legal European initiatives



Anna Gerometta (Milan, IT)

Control of traffic and diesel vehicles to reduce NO2 concentrations in Milan



Andrzej Gula (Krakow, PL)

Household combustion of solid fuels regulations to reduce PM concentrations in Poland


Thiago Herick De Sa (Geneva, CH)

WHO Urban Health Initiative: creating demand for action against air pollution through health knowledge and leadership



Closing of Respirami 3